• 21st century bio leading company

    Developing immunoblot-based proteome analysis technology and antibody detection technology for analysis

Healthcare in the post-genome era

The genome project provided genome (genome) information of humans and other organisms. After transferred to the protein the genome information takes charge of various biological functions.
Proteomics, which studies the proteome, the sum of proteins in vivo, is an important research area in the post genome era and is creating a new paradigm
for the development of the health care field such as diagnosis of diseases and development of new therapeutic agents.




Background of antibody-based proteome analysis

Based on a variety of analytical techniques, Proteomics is expanding into areas to study quantitative analysis of proteome, post-translational modification,
interactions between proteomes, and structural properties of proteome
Due to the complexity of proteome and the wide dynamic range in cellular concentrations present in the sample, the existing gel-based proteomic methods or mass spectrometry based proteomic methods have limitations to observe the appearance of the whole proteome.

The antibody-based proteome analysis method is a method of analyzing a desired proteome using the specificity and sensitivity of an antigen-antibody reaction.
A large antibody collection corresponding to in vivo proteome can be the most efficient method for screening and analyzing the desired proteome.